The toxicity of prolamins arising from oats (avenins) is to date a controversial subject. Differences between avenin and prolamin sequences from wheat, barley and rye determine that these are not detected by Antibody R5, at the same time as providing an argument in favour of the reduced toxicity of oats for coeliac patients. In any case, and despite the lack of consensus in the scientific community, Imbiosis also makes available to its customers a system that is capable of quantifying the amount of avenins contained in a foodstuff.

The Competitive ELISA for oats is a method that is especially indicated for the determination of avenins in all types of foods. This technique is based on the use of a gamma polyclonal antipeptide antibody 3A that is specific for avenins.